Product Datasheet
27 May 2026
Computing System · Compact-Computing-System
NISE 4200
Series: NISE 4200

The Nexcom NISE 4200 is a wide-temperature fanless industrial box PC built on the 6th Generation Intel Core i5-6442EQ (Quad Core, 1.9 GHz, 6 MB cache) or Core i3-6102E (Dual Core, 1.9 GHz, 4 MB cache) BGA embedded processor on the Intel QM170 / HM170 PCH. Two DDR4 SO-DIMM sockets accept up to 32 GB (unbuffered, non-ECC). Storage includes a 2280 / 2240 B+M Key M.2 slot, an mSATA slot and an internal 2.5" SATA HDD/SSD bay. Display reaches three independent outputs — 1 x DVI-D and 2 x DisplayPort 1.2 — covering dual or triple-display production HMIs. Front I/O carries the DC 24 V ±20% input, an ATX power switch, COM1 (RS-232/422/485 BIOS-selectable), 4 x USB 3.0, 2 x USB 2.0, both Gigabit LAN ports (Intel I210-IT + Intel I219-LM with iAMT 11 on the 4200Q-6442EQ SKU) and a line-out audio jack. Rear I/O adds 5 x DB9 for COM2 (RS-232/422/485 auto flow control) plus COM3–COM6 (RS-232) and the 1 x DVI-D port. Internal extras: 1 x USB 2.0 type A, 1 x USB 2.0 box header, 16-channel GPIO pin header (8 x GPO + 8 x GPI, TTL 5 V), on-board TPM 2.0 (SLB9665) for data encryption, two internal mini-PCIe sockets for Wi-Fi / 3.5G / LTE / mSATA and a SIM card socket. The aluminium fanless chassis is rated -20°C to 70°C operating with airflow, 10–93% RH non-condensing, IEC 60068-2-64 / -2-6 vibration and IEC 60068-2-27 shock protection on both HDD and SSD/M.2. CE (EN 55032 / EN 55024) and FCC Class A. OS support: Windows 7 32/64-bit and Windows 10 64-bit. Two SKUs: NISE 4200Q-6442EQ (P/N 10J00420002X0, iAMT) and NISE 4200H-6102E (P/N 10J00420005X0, without iAMT). TSL Automation supplies the Nexcom NISE 4200 worldwide.
Key Features
- Fanless industrial box PC on 6th Gen Intel Core i5-6442EQ (Quad, 1.9 GHz, 6M) or Core i3-6102E (Dual, 1.9 GHz, 4M) BGA
- Intel QM170 / HM170 PCH; turbo-boost disabled by default
- 2 x DDR4 SO-DIMM, supports up to 32 GB (non-ECC, unbuffered)
- Triple independent display: 1 x DVI-D + 2 x DisplayPort 1.2
- Dual GbE: Intel I210-IT (WoL, PXE) + Intel I219-LM with Intel AMT 11 (NISE 4200Q-6442EQ SKU)
- 4 x USB 3.0 (900 mA) + 2 x USB 2.0 (500 mA) on front; 1 x USB 2.0 type A + 1 x USB 2.0 box header internal
- 6 x COM ports: COM1 RS-232/422/485 (BIOS-selectable, front DB9), COM2 RS-232/422/485 auto flow (rear DB9), COM3–6 RS-232 (rear DB9)
- 16-channel GPIO (8 x GPO + 8 x GPI, TTL 5 V) on internal pin header
- On-board TPM 2.0 (SLB9665) for data encryption
- Storage: 1 x 2280/2240 B+M Key M.2 + 1 x mSATA (SATA 3.0) + 1 x 2.5" SATA HDD/SSD
- 2 x internal mini-PCIe (optional Wi-Fi / 3.5G / LTE / mSATA) + 1 x SIM card socket
- 24 V ±20% DC input; AT/ATX power mode (default ATX); optional 24 V / 120 W AC-DC adapter
- Aluminium fanless chassis, -20°C to 70°C operating; 10–93% RH non-condensing
- Dimensions 269 x 157 x 56 mm; gross 2.8 kg, net 2.1 kg
- CE (EN 55032 / EN 55024) + FCC Class A; OS: Windows 7 32/64-bit, Windows 10 64-bit
Technical Specifications
System Information
| CPU Support | 6th Generation Intel Core i5-6442EQ Quad Core 1.9 GHz, 6 MB cache (BGA, NISE 4200Q-6442EQ), 6th Generation Intel Core i3-6102E Dual Core 1.9 GHz, 4 MB cache (BGA, NISE 4200H-6102E), Turbo-boost disabled by default |
|---|---|
| Chipset | Intel QM170 / HM170 PCH |
| System Memory | 2 x DDR4 SO-DIMM, up to 32 GB, unbuffered non-ECC |
| TPM | On-board TPM 2.0 (SLB9665) for data encryption |
| CPU Cooler | Passive (Fanless) |
Storage
| M.2 | 1 x 2280 or 2240 B+M Key M.2 slot |
|---|---|
| mSATA | 1 x mSATA (SATA 3.0) |
| HDD/SSD Bay | 1 x 2.5" SATA HDD or SSD (SATA 3.0) |
Display
| Display Outputs | 1 x DVI-D, 2 x DisplayPort 1.2 |
|---|---|
| Independent Display | Triple (DP + DP + DVI-D), Dual (DP + DVI-D) |
Front I/O
| Power | 24 V ±20% DC input, 1 x ATX power on/off switch |
|---|---|
| Display | 2 x DisplayPort 1.2 |
| Audio | 1 x Line-out |
| Serial | 1 x DB9 COM1 (RS-232/422/485 BIOS-selectable) |
| USB | 4 x USB 3.0 (900 mA per port), 2 x USB 2.0 (500 mA per port) |
| LAN | LAN1: Intel I210-IT GbE (WoL, PXE), LAN2: Intel I219-LM GbE with Intel AMT 11 (NISE 4200Q-6442EQ only) |
| Status LEDs | 2 x LAN active, 2 x GPO status / COM1/2 TX/RX, 1 x HDD access |
Rear I/O
| Serial | 5 x DB9 for COM2 + COM3–COM6, COM2: RS-232/422/485 auto flow control, COM3 / COM4 / COM5 / COM6: RS-232 |
|---|---|
| Display | 1 x DVI-D |
Internal I/O
| USB | 1 x USB 2.0 type A connector, 1 x USB 2.0 box header |
|---|---|
| GPIO | 16 channel: 8 x GPO + 8 x GPI, TTL 5 V level (internal pin header) |
Expansion
| Mini-PCIe | 2 x internal mini-PCIe (optional Wi-Fi / 3.5G / mSATA / LTE) |
|---|---|
| M.2 | 1 x 2280 or 2240 B+M Key M.2 slot |
| SIM | 1 x SIM card socket |
Power Requirement
| Power Mode | AT / ATX power mode (default: ATX) |
|---|---|
| DC Input | 24 V ±20% DC input |
| Power Adapter (Optional) | 24 V / 120 W AC-DC adapter w/o power cord (P/N 7400120023X00) |
Software Support
| OS | Windows 7 32-bit and 64-bit, Windows 10 64-bit |
|---|
Certification
| Certification Information | CE — EN 55032, CE — EN 55024, FCC Class A |
|---|
Mechanical & Environmental
| Dimensions (W x D x H) | 269 x 157 x 56 mm (without wall mount bracket) |
|---|---|
| Gross Weight | 2.8 kg |
| Net Weight | 2.1 kg |
| Construction | Aluminium chassis, fanless |
| Operating Temp. | -20°C to 70°C ambient with airflow (IEC 60068-2-1 / -2-2 / -2-14) |
| Storage Temp. | -20°C to 80°C |
| Humidity | 10–93% relative humidity, non-condensing |
| Shock — HDD | 20 G half sine, 11 ms, IEC 60068-2-27 |
| Shock — M.2 | 50 G half sine, 11 ms, IEC 60068-2-27 |
| Vibration with HDD | Random 0.5 Grms @ 5–500 Hz, IEC 60068-2-64, Sinusoidal 0.5 Grms @ 5–500 Hz, IEC 60068-2-6 |
| Vibration with SSD & M.2 | Random 2 Grms @ 5–500 Hz, IEC 60068-2-64, Sinusoidal 2 Grms @ 5–500 Hz, IEC 60068-2-6 |
Ordering Information
| System | NISE 4200Q-6442EQ (P/N: 10J00420002X0) — 6th Gen Core i5-6442EQ fanless system with iAMT supported, NISE 4200H-6102E (P/N: 10J00420005X0) — 6th Gen Core i3-6102E fanless system without iAMT |
|---|---|
| Options | 24 V / 120 W AC-DC power adapter w/o power cord (P/N 7400120023X00) |