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Product Datasheet

27 May 2026

Computing System · Compact-Computing-System

NISE 4200

Series: NISE 4200

Manufactured byNexcom
Nexcom NISE 4200 6th Gen Core i5/i3 Fanless Industrial PC — Front I/O

The Nexcom NISE 4200 is a wide-temperature fanless industrial box PC built on the 6th Generation Intel Core i5-6442EQ (Quad Core, 1.9 GHz, 6 MB cache) or Core i3-6102E (Dual Core, 1.9 GHz, 4 MB cache) BGA embedded processor on the Intel QM170 / HM170 PCH. Two DDR4 SO-DIMM sockets accept up to 32 GB (unbuffered, non-ECC). Storage includes a 2280 / 2240 B+M Key M.2 slot, an mSATA slot and an internal 2.5" SATA HDD/SSD bay. Display reaches three independent outputs — 1 x DVI-D and 2 x DisplayPort 1.2 — covering dual or triple-display production HMIs. Front I/O carries the DC 24 V ±20% input, an ATX power switch, COM1 (RS-232/422/485 BIOS-selectable), 4 x USB 3.0, 2 x USB 2.0, both Gigabit LAN ports (Intel I210-IT + Intel I219-LM with iAMT 11 on the 4200Q-6442EQ SKU) and a line-out audio jack. Rear I/O adds 5 x DB9 for COM2 (RS-232/422/485 auto flow control) plus COM3–COM6 (RS-232) and the 1 x DVI-D port. Internal extras: 1 x USB 2.0 type A, 1 x USB 2.0 box header, 16-channel GPIO pin header (8 x GPO + 8 x GPI, TTL 5 V), on-board TPM 2.0 (SLB9665) for data encryption, two internal mini-PCIe sockets for Wi-Fi / 3.5G / LTE / mSATA and a SIM card socket. The aluminium fanless chassis is rated -20°C to 70°C operating with airflow, 10–93% RH non-condensing, IEC 60068-2-64 / -2-6 vibration and IEC 60068-2-27 shock protection on both HDD and SSD/M.2. CE (EN 55032 / EN 55024) and FCC Class A. OS support: Windows 7 32/64-bit and Windows 10 64-bit. Two SKUs: NISE 4200Q-6442EQ (P/N 10J00420002X0, iAMT) and NISE 4200H-6102E (P/N 10J00420005X0, without iAMT). TSL Automation supplies the Nexcom NISE 4200 worldwide.

Key Features

  • Fanless industrial box PC on 6th Gen Intel Core i5-6442EQ (Quad, 1.9 GHz, 6M) or Core i3-6102E (Dual, 1.9 GHz, 4M) BGA
  • Intel QM170 / HM170 PCH; turbo-boost disabled by default
  • 2 x DDR4 SO-DIMM, supports up to 32 GB (non-ECC, unbuffered)
  • Triple independent display: 1 x DVI-D + 2 x DisplayPort 1.2
  • Dual GbE: Intel I210-IT (WoL, PXE) + Intel I219-LM with Intel AMT 11 (NISE 4200Q-6442EQ SKU)
  • 4 x USB 3.0 (900 mA) + 2 x USB 2.0 (500 mA) on front; 1 x USB 2.0 type A + 1 x USB 2.0 box header internal
  • 6 x COM ports: COM1 RS-232/422/485 (BIOS-selectable, front DB9), COM2 RS-232/422/485 auto flow (rear DB9), COM3–6 RS-232 (rear DB9)
  • 16-channel GPIO (8 x GPO + 8 x GPI, TTL 5 V) on internal pin header
  • On-board TPM 2.0 (SLB9665) for data encryption
  • Storage: 1 x 2280/2240 B+M Key M.2 + 1 x mSATA (SATA 3.0) + 1 x 2.5" SATA HDD/SSD
  • 2 x internal mini-PCIe (optional Wi-Fi / 3.5G / LTE / mSATA) + 1 x SIM card socket
  • 24 V ±20% DC input; AT/ATX power mode (default ATX); optional 24 V / 120 W AC-DC adapter
  • Aluminium fanless chassis, -20°C to 70°C operating; 10–93% RH non-condensing
  • Dimensions 269 x 157 x 56 mm; gross 2.8 kg, net 2.1 kg
  • CE (EN 55032 / EN 55024) + FCC Class A; OS: Windows 7 32/64-bit, Windows 10 64-bit

Technical Specifications

System Information

CPU Support6th Generation Intel Core i5-6442EQ Quad Core 1.9 GHz, 6 MB cache (BGA, NISE 4200Q-6442EQ), 6th Generation Intel Core i3-6102E Dual Core 1.9 GHz, 4 MB cache (BGA, NISE 4200H-6102E), Turbo-boost disabled by default
ChipsetIntel QM170 / HM170 PCH
System Memory2 x DDR4 SO-DIMM, up to 32 GB, unbuffered non-ECC
TPMOn-board TPM 2.0 (SLB9665) for data encryption
CPU CoolerPassive (Fanless)

Storage

M.21 x 2280 or 2240 B+M Key M.2 slot
mSATA1 x mSATA (SATA 3.0)
HDD/SSD Bay1 x 2.5" SATA HDD or SSD (SATA 3.0)

Display

Display Outputs1 x DVI-D, 2 x DisplayPort 1.2
Independent DisplayTriple (DP + DP + DVI-D), Dual (DP + DVI-D)

Front I/O

Power24 V ±20% DC input, 1 x ATX power on/off switch
Display2 x DisplayPort 1.2
Audio1 x Line-out
Serial1 x DB9 COM1 (RS-232/422/485 BIOS-selectable)
USB4 x USB 3.0 (900 mA per port), 2 x USB 2.0 (500 mA per port)
LANLAN1: Intel I210-IT GbE (WoL, PXE), LAN2: Intel I219-LM GbE with Intel AMT 11 (NISE 4200Q-6442EQ only)
Status LEDs2 x LAN active, 2 x GPO status / COM1/2 TX/RX, 1 x HDD access

Rear I/O

Serial5 x DB9 for COM2 + COM3–COM6, COM2: RS-232/422/485 auto flow control, COM3 / COM4 / COM5 / COM6: RS-232
Display1 x DVI-D

Internal I/O

USB1 x USB 2.0 type A connector, 1 x USB 2.0 box header
GPIO16 channel: 8 x GPO + 8 x GPI, TTL 5 V level (internal pin header)

Expansion

Mini-PCIe2 x internal mini-PCIe (optional Wi-Fi / 3.5G / mSATA / LTE)
M.21 x 2280 or 2240 B+M Key M.2 slot
SIM1 x SIM card socket

Power Requirement

Power ModeAT / ATX power mode (default: ATX)
DC Input24 V ±20% DC input
Power Adapter (Optional)24 V / 120 W AC-DC adapter w/o power cord (P/N 7400120023X00)

Software Support

OSWindows 7 32-bit and 64-bit, Windows 10 64-bit

Certification

Certification InformationCE — EN 55032, CE — EN 55024, FCC Class A

Mechanical & Environmental

Dimensions (W x D x H)269 x 157 x 56 mm (without wall mount bracket)
Gross Weight2.8 kg
Net Weight2.1 kg
ConstructionAluminium chassis, fanless
Operating Temp.-20°C to 70°C ambient with airflow (IEC 60068-2-1 / -2-2 / -2-14)
Storage Temp.-20°C to 80°C
Humidity10–93% relative humidity, non-condensing
Shock — HDD20 G half sine, 11 ms, IEC 60068-2-27
Shock — M.250 G half sine, 11 ms, IEC 60068-2-27
Vibration with HDDRandom 0.5 Grms @ 5–500 Hz, IEC 60068-2-64, Sinusoidal 0.5 Grms @ 5–500 Hz, IEC 60068-2-6
Vibration with SSD & M.2Random 2 Grms @ 5–500 Hz, IEC 60068-2-64, Sinusoidal 2 Grms @ 5–500 Hz, IEC 60068-2-6

Ordering Information

SystemNISE 4200Q-6442EQ (P/N: 10J00420002X0) — 6th Gen Core i5-6442EQ fanless system with iAMT supported, NISE 4200H-6102E (P/N: 10J00420005X0) — 6th Gen Core i3-6102E fanless system without iAMT
Options24 V / 120 W AC-DC power adapter w/o power cord (P/N 7400120023X00)

Authorised distributor, India

TSL Automation Solutions

Mumbai, India

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© 2026 TSL Automation Solutions. Specifications subject to change without notice. This datasheet was generated from manufacturer-supplied technical data.