Nexcom · Computing System
NISE 4200








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Highlights
- Fanless industrial box PC on 6th Gen Intel Core i5-6442EQ (Quad, 1.9 GHz, 6M) or Core i3-6102E (Dual, 1.9 GHz, 4M) BGA
- Intel QM170 / HM170 PCH; turbo-boost disabled by default
- 2 x DDR4 SO-DIMM, supports up to 32 GB (non-ECC, unbuffered)
- Triple independent display: 1 x DVI-D + 2 x DisplayPort 1.2
- Dual GbE: Intel I210-IT (WoL, PXE) + Intel I219-LM with Intel AMT 11 (NISE 4200Q-6442EQ SKU)
- 4 x USB 3.0 (900 mA) + 2 x USB 2.0 (500 mA) on front; 1 x USB 2.0 type A + 1 x USB 2.0 box header internal
- 6 x COM ports: COM1 RS-232/422/485 (BIOS-selectable, front DB9), COM2 RS-232/422/485 auto flow (rear DB9), COM3–6 RS-232 (rear DB9)
- 16-channel GPIO (8 x GPO + 8 x GPI, TTL 5 V) on internal pin header
- On-board TPM 2.0 (SLB9665) for data encryption
- Storage: 1 x 2280/2240 B+M Key M.2 + 1 x mSATA (SATA 3.0) + 1 x 2.5" SATA HDD/SSD
- 2 x internal mini-PCIe (optional Wi-Fi / 3.5G / LTE / mSATA) + 1 x SIM card socket
- 24 V ±20% DC input; AT/ATX power mode (default ATX); optional 24 V / 120 W AC-DC adapter
- Aluminium fanless chassis, -20°C to 70°C operating; 10–93% RH non-condensing
- Dimensions 269 x 157 x 56 mm; gross 2.8 kg, net 2.1 kg
- CE (EN 55032 / EN 55024) + FCC Class A; OS: Windows 7 32/64-bit, Windows 10 64-bit
Product Description
The Nexcom NISE 4200 is a wide-temperature fanless industrial box PC built on the 6th Generation Intel Core i5-6442EQ (Quad Core, 1.9 GHz, 6 MB cache) or Core i3-6102E (Dual Core, 1.9 GHz, 4 MB cache) BGA embedded processor on the Intel QM170 / HM170 PCH.
Two DDR4 SO-DIMM sockets accept up to 32 GB (unbuffered, non-ECC). Storage includes a 2280 / 2240 B+M Key M.2 slot, an mSATA slot and an internal 2.5" SATA HDD/SSD bay. Display reaches three independent outputs — 1 x DVI-D and 2 x DisplayPort 1.2 — covering dual or triple-display production HMIs.
Front I/O carries the DC 24 V ±20% input, an ATX power switch, COM1 (RS-232/422/485 BIOS-selectable), 4 x USB 3.0, 2 x USB 2.0, both Gigabit LAN ports (Intel I210-IT + Intel I219-LM with iAMT 11 on the 4200Q-6442EQ SKU) and a line-out audio jack.
Rear I/O adds 5 x DB9 for COM2 (RS-232/422/485 auto flow control) plus COM3–COM6 (RS-232) and the 1 x DVI-D port.
Internal extras: 1 x USB 2.0 type A, 1 x USB 2.0 box header, 16-channel GPIO pin header (8 x GPO + 8 x GPI, TTL 5 V), on-board TPM 2.0 (SLB9665) for data encryption, two internal mini-PCIe sockets for Wi-Fi / 3.5G / LTE / mSATA and a SIM card socket.
The aluminium fanless chassis is rated -20°C to 70°C operating with airflow, 10–93% RH non-condensing, IEC 60068-2-64 / -2-6 vibration and IEC 60068-2-27 shock protection on both HDD and SSD/M.2. CE (EN 55032 / EN 55024) and FCC Class A. OS support: Windows 7 32/64-bit and Windows 10 64-bit.
Two SKUs: NISE 4200Q-6442EQ (P/N 10J00420002X0, iAMT) and NISE 4200H-6102E (P/N 10J00420005X0, without iAMT). TSL Automation supplies the Nexcom NISE 4200 worldwide.
Technical Specifications
What is NISE 4200?
The NISE 4200 is a computing system manufactured by Nexcom, designed specifically for compact-computing-system applications. It features processor of 6th Generation Intel Core i5-6442EQ Quad Core 1.9 GHz, 6 MB cache (BGA, NISE 4200Q-6442EQ), 6th Generation …, display of 1 x DVI-D, 2 x DisplayPort 1.2 and memory of 2 x DDR4 SO-DIMM, up to 32 GB, unbuffered non-ECC. The Nexcom NISE 4200 is a wide-temperature fanless industrial box PC built on the 6th Generation Intel Core i5-6442EQ (Quad Core, 1.9 GHz, 6 MB cache) or Core i3-6102E (Dual Core, 1.9 GHz, 4 MB cache) BGA embedded processor on the Intel QM170 / HM170 PCH. Two DDR4 SO-DIMM sockets accept up to 32 GB (unbuffered, non-ECC). Storage includes a 2280 / 2240 B+M Key M.2 slot, an mSATA slot and an internal 2.5" SATA HDD/SSD bay. Display reaches three independent outputs — 1 x DVI-D and 2 x DisplayPort 1.2 — covering dual or triple-display production HMIs. Front I/O carries the DC 24 V ±20% input, an ATX power switch, COM1 (RS-232/422/485 BIOS-selectable), 4 x USB 3.0, 2 x USB 2.0, both Gigabit LAN ports (Intel I210-IT + Intel I219-LM with iAMT 11 on the 4200Q-6442EQ SKU) and a line-out audio jack. Rear I/O adds 5 x DB9 for COM2 (RS-232/422/485 auto flow control) plus COM3–COM6 (RS-232) and the 1 x DVI-D port. Internal extras: 1 x USB 2.0 type A, 1 x USB 2.0 box header, 16-channel GPIO pin header (8 x GPO + 8 x GPI, TTL 5 V), on-board TPM 2.0 (SLB9665) for data encryption, two internal mini-PCIe sockets for Wi-Fi / 3.5G / LTE / mSATA and a SIM card socket. The aluminium fanless chassis is rated -20°C to 70°C operating with airflow, 10–93% RH non-condensing, IEC 60068-2-64 / -2-6 vibration and IEC 60068-2-27 shock protection on both HDD and SSD/M.2. CE (EN 55032 / EN 55024) and FCC Class A. OS support: Windows 7 32/64-bit and Windows 10 64-bit. Two SKUs: NISE 4200Q-6442EQ (P/N 10J00420002X0, iAMT) and NISE 4200H-6102E (P/N 10J00420005X0, without iAMT). TSL Automation supplies the Nexcom NISE 4200 worldwide.
Key Features & Benefits
- Fanless industrial box PC on 6th Gen Intel Core i5-6442EQ (Quad, 1.9 GHz, 6M) or Core i3-6102E (Dual, 1.9 GHz, 4M) BGA
- Intel QM170 / HM170 PCH; turbo-boost disabled by default
- 2 x DDR4 SO-DIMM, supports up to 32 GB (non-ECC, unbuffered)
- Triple independent display: 1 x DVI-D + 2 x DisplayPort 1.2
- Dual GbE: Intel I210-IT (WoL, PXE) + Intel I219-LM with Intel AMT 11 (NISE 4200Q-6442EQ SKU)
- 4 x USB 3.0 (900 mA) + 2 x USB 2.0 (500 mA) on front; 1 x USB 2.0 type A + 1 x USB 2.0 box header internal
- 6 x COM ports: COM1 RS-232/422/485 (BIOS-selectable, front DB9), COM2 RS-232/422/485 auto flow (rear DB9), COM3–6 RS-232 (rear DB9)
- 16-channel GPIO (8 x GPO + 8 x GPI, TTL 5 V) on internal pin header
- On-board TPM 2.0 (SLB9665) for data encryption
- Storage: 1 x 2280/2240 B+M Key M.2 + 1 x mSATA (SATA 3.0) + 1 x 2.5" SATA HDD/SSD
- 2 x internal mini-PCIe (optional Wi-Fi / 3.5G / LTE / mSATA) + 1 x SIM card socket
- 24 V ±20% DC input; AT/ATX power mode (default ATX); optional 24 V / 120 W AC-DC adapter
- Aluminium fanless chassis, -20°C to 70°C operating; 10–93% RH non-condensing
- Dimensions 269 x 157 x 56 mm; gross 2.8 kg, net 2.1 kg
- CE (EN 55032 / EN 55024) + FCC Class A; OS: Windows 7 32/64-bit, Windows 10 64-bit
Applications & Use Cases
The NISE 4200 is ideal for various industrial automation applications:
- Dust-sensitive environments and silent operation requirements
- DC-powered industrial installations and mobile applications
- Extreme temperature environments and outdoor installations
- Wireless connectivity and remote monitoring applications
- Legacy equipment integration and serial communication
- High-performance computing and data processing tasks
- Peripheral device connectivity and data transfer
- Memory-intensive applications and multitasking